What is the compounded dose limit for codeine or hydrocodone products to be classified as Schedule 3 when compounded with a non-narcotic ingredient?

The compounded dose limit for codeine or hydrocodone products to be classified as Schedule 3 when combined with a non-narcotic ingredient is indeed set at 1.8 grams per 100 milliliters. This particular threshold is outlined in the federal regulations that define how these narcotic substances can be compounded for clinical use.

In this context, the classification as Schedule 3 is important because it reflects the potential for abuse relative to narcotics classified as Schedule 2. The combination of codeine or hydrocodone with non-narcotic ingredients does allow for a more lenient regulatory framework—provided that the compounded formulation adheres to the stipulated dosage limits.

The specificity of the 1.8 grams per 100 milliliters serves as a safeguard. It ensures that the compounded product does not exceed a threshold where the potential for abuse or misuse may increase significantly. Understanding these parameters is crucial for pharmacists working with controlled substances to ensure compliance with both state and federal laws.